EN
Shangfeng Wang
Analytical Chemistry
Tenure track Professor
Room 632, Advanced Materials Building, Department of Chemistry, Fudan University, 2005 Songhu Road, Yangpu District, Shanghai 200438, China
Research Interests
Molecular probes in biological systems, including fluorescent dyes, fluorescent proteins, photoacoustic/photothermal probes，lanthanide complexes, photocatalytic organic probes etc.
Shortwave infrared in vivo imaging technologies, including AI-driven multispectral imaging, fluorescence-guided surgery, neural activity imaging, intravital microscopy etc.
Academic Appointments
Associate Editor, Frontiers in Chemistry
Editorial Board (Junior Member), Nano-Micro Letters
Editorial Board (Junior Member), Smart Molecules
Prizes and awards
2025 National Natural Science Foundation of China, Young Scientists Fund (Category B)
2023 The First Prize of Natural Science of Chinese Rare Earth Society (Fifth author)
2023 Zhuoxue Talent Program of Fudan University
2023 Ring-Star Program of Science and Technology Commission of Shanghai Municipality
2021 Fudan Outstanding Postdocs
2020 Shanghai Super Postdoc Program
2019 Shanghai Outstanding Graduates
2012 Outstanding Students in Science and Engineering of ECUST
Biography
Mar. 2022--NowTenure track Professor, Department of Chemistry, Fudan University, Shanghai, China
Jul.2019--Feb.2022Postdocs (Advisor: Prof. Fan Zhang), Department of Chemistry, Fudan University, Shanghai, China
Sep.2016--Jun.2019Ph.D in Analytical Chemistry, Department of Chemistry, Fudan University, Shanghai, China
Sep.2012--Mar.2015M.Eng. in Materials Engineering, College of Materials Science and Engineering, East China University of Science and Technology (ECUST), Shanghai, China
Sep.2008--Jul.2012B.Sc. in Polymer Materials Science and Engineering, College of Materials Science and Engineering, East China University of Science and Technology (ECUST), Shanghai, China
Key Publications
Wu, B.+; Zhang, L.+; Yan, K.; Mei, M.; Wu, W.; He, Z.; Wang, S.*; Zhang, F.* Electronic-Symmetry-Tuned Emission Beyond 1500 nm in Erbium(III)-Phthalocyanine Complexes for High-Resolution In Vivo Biosensing. J. Am. Chem. Soc.2025. DOI: 10.1021/jacs.5c13688.
Zhang, L.+; Cheng, R.+; He, Z.; Mei, M.; Wu, B.; Tan, W.*; Yan, B.*; Wang, S.*; Zhang, F.* Excitation-encoded single-emission shortwave infrared lanthanide fluorophore palette for real-time in vivo multispectral imaging. Nat. Photon. 2025. 19 (11), 1209-1218.
Wu, W.; Yan. K.; He, Z.; Zhang, L.; Dong Y.; Wu, B.; Liu, H.; Wang, S.*; Zhang, F.*, 2X-Rhodamine: A Bright and Fluorogenic Scaffold for Developing Near-Infrared Chemigenetic Indicators. J. Am. Chem. Soc.2024, 146 (16), 11570-11576.
Yan, K.+; Hu, Z.+; Yu, P.; He, Z.; Chen, Y.; Chen, J.; Sun, H.*; Wang, S.*; Zhang, F.*, Ultra-photostable small-molecule dyes facilitate near-infrared biophotonics. Nat. Commun. 2024, 15 (1), 2593.
Shi, B.; Zhang, L.; Yan, K.; Ming, J.; Chen, Z.-H.; Chen, Y.; He, H.; Zhang, H.; Wang, L.; Wang, S.*; et al. Efficient and stable NIR-II phosphorescence of metallophilicmolecular oligomers for in vivo single-cell tracking and time-resolved imaging. Angew. Chem. Int. Ed.2024, 63 (42), e202410118.
Mei, M.; Wu, B.; Wang, S.*; Zhang, F.* Lanthanide-dye hybrid luminophores for advanced NIR-II bioimaging. Curr. Opin. Chem. Biol. 2024, 80, 102469.
Yang, Y.; Sun, C.; Wang, S.*; Yan, K.; Zhao, M.; Wu, B.; Zhang, F.*, Counterion-paired Bright Heptamethine Fluorophores with NIR-II Excitation and Emission Enable Multiplexed Biomedical Imaging. Angew. Chem. Int. Ed. 2022, 61 (24), e202117436.
Yu, P.; Yan, K.; Wang, S.*; Yao, C.; Lei, Z.; Tang, Y.; Zhang, F.* NIR-II Dyad-Doped Ratiometric Nanosensor with Enhanced Spectral Fidelity in Biological Media for In Vivo Biosensing. Nano Lett.2022, 22 (23), 9732–9740.
Wang, T.+; Wang, S.+*; Liu, Z.+; He, Z.; Yu, P.; Zhao, M.; Zhang, H.; Lu, L.; Wang, Z.; Wang, Z.; Zhang, W.*; Fan, Y.; Sun, C.; Zhao, D.; Liu, W.; Bünzli, J.-C. G.; Zhang, F.*, A hybrid erbium(III)–bacteriochlorin near-infrared probe for multiplexed biomedical imaging. Nat. Mater.2021, 20 (11), 1571-1578.
Wang, S.; Zhang, F.*, Azo Pigments Make Raman Spectral Multiplexing More Sensitive. ACS Cent. Sci.2021, 7 (5), 709-711.
He, Y.+; Wang, S.+*; Yu, P.+; Yan, K.; Ming, J.; Yao, C.; He, Z.; El-Toni, A. M.; Khan, A.; Zhu, X.; Sun, C.; Lei, Z.; Zhang, F.*, NIR-II cell endocytosis-activated fluorescent probes for in vivo high-contrast bioimaging diagnostics. Chem. Sci. 2021, 12 (31), 10474-10482.
Wang, S.+; Li, B.+; Zhang, F.*, Molecular Fluorophores for Deep-Tissue Bioimaging. ACS Cent. Sci. 2020, 6 (8), 1302-1316.
Wang, S.; Liu, L.; Fan, Y.; El-Toni, A. M.; Alhoshan, M. S.; Li, D.; Zhang, F.*, In Vivo High-resolution Ratiometric Fluorescence Imaging of Inflammation Using NIR-II Nanoprobes with 1550 nm Emission. Nano Lett.2019, 19 (4), 2418-2427.
Wang, S.; Fan, Y.; Li, D.; Sun, C.; Lei, Z.; Lu, L.; Wang, T.; Zhang, F.*, Anti-quenching NIR-II molecular fluorophores for in vivo high-contrast imaging and pH sensing. Nat. Commun. 2019, 10 (1), 1058.
